ARG64294

anti-DBP5 / DDX19 antibody

anti-DBP5 / DDX19 antibody for Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes DBP5 / DDX19
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application WB
Specificity This antibody is expected to recognise DDX19A (NP_060802.1) and all reported isoforms of DDX19B (NP_009173.1, NP_001014451.1 and NP_001014449.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name DBP5 / DDX19
Immunogen C-DLPVDKDGNPDNETY
Conjugation Un-conjugated
Alternate Names DEAD box protein 19B; DDX19; EC 3.6.4.13; RNAh; DBP5; DEAD box RNA helicase DEAD5; ATP-dependent RNA helicase DDX19B

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.5 - 1.5 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11269 Human DDX19B

Swiss-port # Q9UMR2 Human ATP-dependent RNA helicase DDX19B

Gene Symbol DDX19B
Gene Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins. [UniProt]
Research Area Signaling Transduction antibody
Calculated MW 54 kDa