ARG41744
anti-DDX6 antibody
anti-DDX6 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DDX6 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DDX6 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 400 to the C-terminus of Human DDX6 (NP_001244120.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Probable ATP-dependent RNA helicase DDX6; DEAD box protein 6; Oncogene RCK; ATP-dependent RNA helicase p54; EC 3.6.4.13; RCK; P54; HLR2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Rat spleen | ||||||||
| Observed Size | ~ 54 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P26196 Human Probable ATP-dependent RNA helicase DDX6 Swiss-port # P54823 Mouse Probable ATP-dependent RNA helicase DDX6 |
|---|---|
| Gene Symbol | DDX6 |
| Gene Full Name | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| Background | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
| Function | In the process of mRNA degradation, may play a role in mRNA decapping. [UniProt] |
| Cellular Localization | Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Upon cellular stress, relocalizes to stress granules (PubMed:26184334). [UniProt] |
| Calculated MW | 54 kDa |
| PTM | Sumoylated (PubMed:26184334). [UniProt] |
