ARG54331
anti-DFFB / DFF40 / CAD antibody
anti-DFFB / DFF40 / CAD antibody for Western blot,Immunohistochemistry and Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes DFFB / DFF40 / CAD |
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Tested Reactivity | Ms |
Tested Application | IHC, WB |
Specificity | This antibody recognizes full-length mouse DFFB / DFF40 / CAD (40kDa). |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DFFB / DFF40 / CAD |
Antigen Species | Mouse |
Immunogen | Peptide corresponding to aa 314-329 of mouse DFFB / DFF40 / CAD (accession no. O54788). |
Conjugation | Un-conjugated |
Protein Full Name | DNA fragmentation factor subunit beta |
Alternate Names | Caspase-activated DNase; DFF40; DFF-40; Caspase-activated deoxyribonuclease; DNA fragmentation factor 40 kDa subunit; Caspase-activated nuclease; CPAN; DNA fragmentation factor subunit beta; DFF2; CAD |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | Mouse lung and kidney |
Properties
Form | Liquid |
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Purification | Immunoaffinity chroma-tography |
Buffer | PBS (pH 7.4) and 0.02% Sodium azide |
Preservative | 0.02% Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # O54788 Mouse DNA fragmentation factor subunit beta |
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Gene Symbol | Dffb |
Gene Full Name | DNA fragmentation factor, beta subunit |
Background | Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD (caspase activated deoxyribo-nuclease). Activation of CAD/DFF40, which causes DNA degradation, is the hallmark of apoptotic cell death. |
Function | Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. [UniProt] |
Cellular Localization | Cytoplasm, Nucleus [uniprot] |
Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody |
Calculated MW | 39 kDa |