ARG57278
anti-DGAT1 antibody
anti-DGAT1 antibody for Western blot and Human,Mouse
Overview
Product Description | Rabbit Polyclonal antibody recognizes DGAT1 |
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Tested Reactivity | Hu, Ms |
Predict Reactivity | Rat |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DGAT1 |
Antigen Species | Human |
Immunogen | Recombinant protein of Human DGAT1. |
Conjugation | Un-conjugated |
Alternate Names | ARGP1; Diacylglycerol O-acyltransferase 1; ARAT; Retinol O-fatty-acyltransferase; DGAT; EC 2.3.1.76; ACAT-related gene product 1; Acyl-CoA retinol O-fatty-acyltransferase; Diglyceride acyltransferase; DIAR7; EC 2.3.1.20 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | HL-60 |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # O75907 Human Diacylglycerol O-acyltransferase 1 Swiss-port # Q9Z2A7 Mouse Diacylglycerol O-acyltransferase 1 |
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Gene Symbol | DGAT1 |
Gene Full Name | diacylglycerol O-acyltransferase 1 |
Background | This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013] |
Function | Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. [UniProt] |
Calculated MW | 55 kDa |