ARG58094
anti-DHRS2 antibody
anti-DHRS2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes DHRS2 |
---|---|
Tested Reactivity | Hu, Ms, Rat |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DHRS2 |
Antigen Species | Human |
Immunogen | Recombinant fusion protein corresponding to aa. 1-300 of Human DHRS2 (NP_878912.1). |
Conjugation | Un-conjugated |
Alternate Names | HEP27; Protein D; Dicarbonyl reductase HEP27; EC 1.1.1.-; Dehydrogenase/reductase SDR family member 2, mitochondrial; SDR25C1; Short chain dehydrogenase/reductase family 25C member 1 |
Application Instructions
Application Suggestion |
|
||||||
---|---|---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | MCF7 | ||||||
Observed Size | ~ 33 kDa |
Properties
Form | Liquid |
---|---|
Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q13268 Human Dehydrogenase/reductase SDR family member 2, mitochondrial |
---|---|
Gene Symbol | DHRS2 |
Gene Full Name | dehydrogenase/reductase (SDR family) member 2 |
Function | Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. [UniProt] |
Cellular Localization | Mitochondrion matrix, Nucleus. [UniProt] |
Calculated MW | 30 kDa |