ARG41172
anti-DHX38 / PRP16 antibody
anti-DHX38 / PRP16 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DHX38 / PRP16 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DHX38 / PRP16 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1133-1227 of Human DHX38 / PRP16 (NP_054722.2). |
| Conjugation | Un-conjugated |
| Alternate Names | DDX38; PRPF16; PRP16; DEAH box protein 38; Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; EC 3.6.4.13; ATP-dependent RNA helicase DHX38 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse testis | ||||
| Observed Size | 140 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q92620 Human Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 |
|---|---|
| Gene Symbol | DHX38 |
| Gene Full Name | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| Background | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008] |
| Function | Probable ATP-binding RNA helicase involved in pre-mRNA splicing. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 141 kDa |
