ARG58495
anti-DHX8 antibody
anti-DHX8 antibody for Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes DHX8 |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DHX8 |
Antigen Species | Human |
Immunogen | Recombinant fusion protein corresponding to aa. 1001-1220 of Human DHX8 (NP_004932.1). |
Conjugation | Un-conjugated |
Alternate Names | PRP22; RNA helicase HRH1; DEAH box protein 8; PRPF22; ATP-dependent RNA helicase DHX8; EC 3.6.4.13; HRH1; DDX8 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | HeLa | ||||
Observed Size | 150 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | DHX8 |
Gene Full Name | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
Background | This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
Function | Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [UniProt] |
Cellular Localization | Nucleus,. [UniProt] |
Calculated MW | 139 kDa |