ARG44810
anti-DMXL2 antibody
anti-DMXL2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes DMXL2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | DMXL2 |
| Antigen Species | Human |
| Epitope | KNFVDKINLI ERKLFFTTAN AHFKVGCPVL ALEVLSKIPK VTKTSALSAK KDQPDFISHR MDDVPSHSKA LSDGNGSSGI EWSNVTSSQY DWSQPIVKVD EEPLNLDWGE DHDSALDEEE DDAVGLVMKS TDAREKDKQS DQKASDPNML LTPQEEDDPE GDTEVDVIAE QLKFRACLKI LMTELRTLAT GYEVDGGKLR FQLYNWLEKE IAALHEICNH ESVIKEYSSK TYSKVESDLL DQEEMVDKPD IGSYERHQIE RRRLQAKREH |
| Conjugation | Un-conjugated |
| Alternate Names | DMXL2; Dmx Like 2; KIAA0856; DFNA71; RC3; DmX-Like Protein 2; Rabconnectin-3; Rabconnectin 3; EIEE81; DEE81; PEPNS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | DMXL2 |
|---|---|
| Gene Full Name | Dmx Like 2 |
| Background | This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines (PMID:20810660). A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| Function | Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes. [Uniprot] |
| Cellular Localization | Cytoplasmic vesicle, Membrane, Synapse. [Uniprot] |
| PTM | Phosphoprotein. [Uniprot] |
