ARG41019

anti-DNAJC19 antibody

anti-DNAJC19 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes DNAJC19
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DNAJC19
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-116 of Human DNAJC19 (NP_660304.1).
Conjugation Un-conjugated
Alternate Names TIM14; TIMM14; PAM18; Mitochondrial import inner membrane translocase subunit TIM14; DnaJ homolog subfamily C member 19

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HT1080
Observed Size 12 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 131118 Human DNAJC19

GeneID: 67713 Mouse DNAJC19

Swiss-port # Q96DA6 Human Mitochondrial import inner membrane translocase subunit TIM14

Swiss-port # Q9CQV7 Mouse Mitochondrial import inner membrane translocase subunit TIM14

Gene Symbol DNAJC19
Gene Full Name DnaJ (Hsp40) homolog, subfamily C, member 19
Background The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]
Function Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). [UniProt]
Cellular Localization Mitochondrion inner membrane; Single-pass membrane protein. [UniProt]
Calculated MW 12 kDa