ARG41019
anti-DNAJC19 antibody
anti-DNAJC19 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DNAJC19 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DNAJC19 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-116 of Human DNAJC19 (NP_660304.1). |
| Conjugation | Un-conjugated |
| Alternate Names | TIM14; TIMM14; PAM18; Mitochondrial import inner membrane translocase subunit TIM14; DnaJ homolog subfamily C member 19 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HT1080 | ||||||||
| Observed Size | 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96DA6 Human Mitochondrial import inner membrane translocase subunit TIM14 Swiss-port # Q9CQV7 Mouse Mitochondrial import inner membrane translocase subunit TIM14 |
|---|---|
| Gene Symbol | DNAJC19 |
| Gene Full Name | DnaJ (Hsp40) homolog, subfamily C, member 19 |
| Background | The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012] |
| Function | Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). [UniProt] |
| Cellular Localization | Mitochondrion inner membrane; Single-pass membrane protein. [UniProt] |
| Calculated MW | 12 kDa |
