ARG59901
anti-DOK4 antibody
anti-DOK4 antibody for Western blot,ICC/IF and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DOK4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DOK4 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 240-326 of Human DOK4 (NP_060580.2). |
| Conjugation | Un-conjugated |
| Alternate Names | IRS5; Docking protein 4; Insulin receptor substrate 5; Downstream of tyrosine kinase 4; IRS-5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | MCF7 | ||||||
| Observed Size | 37 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DOK4 |
| Gene Full Name | docking protein 4 |
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt] |
| Calculated MW | 37 kDa |
| PTM | Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation. [UniProt] |
