ARG63760

anti-DPP10 antibody

anti-DPP10 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody

Overview

Product Description Goat Polyclonal antibody recognizes DPP10
Tested Reactivity Hu
Predict Reactivity Cow, Dog
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise both reported isoforms (NP_065919.2 and NP_001004360.2).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name DPP10
Antigen Species Human
Immunogen C-DEGHNVSEKSKYHL
Conjugation Un-conjugated
Alternate Names Inactive dipeptidyl peptidase 10; Dipeptidyl peptidase-like protein 2; DPRP3; DPPY; DPRP-3; Dipeptidyl peptidase IV-related protein 3; DPP X; DPL2; Dipeptidyl peptidase X

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WB0.1 - 0.3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 57628 Human DPP10

Swiss-port # Q8N608 Human Inactive dipeptidyl peptidase 10

Background This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody
Calculated MW 91 kDa
PTM N-glycosylation is important for cell surface expression, specially at Asn-257, which is crucial.