ARG58512
anti-DRD1 / Dopamine Receptor D1 antibody
anti-DRD1 / Dopamine Receptor D1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DRD1 / Dopamine Receptor D1 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Hm |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DRD1 / Dopamine Receptor D1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to a sequence in the middle region of Human DRD1 (221-242aa AQKQIRRIAALERAAVHAKNCQ), different from the related Rat and Mouse sequences by one amino acid. |
| Conjugation | Un-conjugated |
| Alternate Names | DADR; DRD1A; D(1A) dopamine receptor; Dopamine D1 receptor |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DRD1 |
| Gene Full Name | dopamine receptor D1 |
| Background | This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008] |
| Function | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. [UniProt] |
| Calculated MW | 49 kDa |
