ARG11043

anti-DRD2 / Dopamine Receptor D2 antibody

anti-DRD2 / Dopamine Receptor D2 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2
Tested Reactivity Hu, Rat
Tested Application ELISA, ICC/IF, IHC-P, IP, WB
Specificity The antibody has no cross reactivity to D1 receptor (9% homology), D3 receptor (18% homology), D4 receptor (27% homology) and D5 receptor (9% homology).
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DRD2 / Dopamine Receptor D2
Antigen Species Human
Immunogen Synthetic peptide from Human Dopamine D2 receptor.
Conjugation Un-conjugated
Alternate Names D2R; D2DR; D(2) dopamine receptor; Dopamine D2 receptor

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA1:50000
ICC/IF1:200
IHC-P1:200
IP1:200
WB1:1000 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, cryo-protective agents, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.55 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1813 Human DRD2

GeneID: 24318 Rat DRD2

Swiss-port # P14416 Human D(2) dopamine receptor

Swiss-port # P61169 Rat D(2) dopamine receptor

Gene Symbol DRD2
Gene Full Name dopamine receptor D2
Background This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein [UniProt]
Calculated MW 51 kDa