ARG55435

anti-DRD2 / Dopamine Receptor D2 antibody

anti-DRD2 / Dopamine Receptor D2 antibody for Western blot and Human,Mouse

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DRD2 / Dopamine Receptor D2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 307-336 (C-terminus) of Human DRD2.
Conjugation Un-conjugated
Alternate Names D2R; D2DR; D(2) dopamine receptor; Dopamine D2 receptor

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human brain

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 13489 Mouse DRD2

GeneID: 1813 Human DRD2

Swiss-port # P14416 Human D(2) dopamine receptor

Swiss-port # P61168 Mouse D(2) dopamine receptor

Gene Symbol DRD2
Gene Full Name dopamine receptor D2
Background This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. [UniProt]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 51 kDa