ARG44816
anti-DTX3L antibody
anti-DTX3L antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes DTX3L |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | DTX3L |
| Antigen Species | Human |
| Epitope | RVRRKLESYF QSSKSSGGGE CTVSTQEHEA PGTFRVEFSE RAAKERVLKK GEHQILVDEK PVPIFLVPTE NSIKKNTRPQ ISSLTQSQAE TPSGDMHQHE |
| Conjugation | Un-conjugated |
| Alternate Names | DTX3L; Deltex E3 Ubiquitin Ligase 3L; BBAP; RNF143; RING-Type E3 Ubiquitin Transferase DTX3L; B-Lymphoma- And BAL-Associated Protein; E3 Ubiquitin-Protein Ligase DTX3L; Rhysin-2; Rhysin2; Deltex 3 Like, E3 Ubiquitin Ligase; Deltex 3-Like (Drosophila); Protein Deltex-3-Like; Deltex 3-Like; EC 2.3.2.27; Rhysin 2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | DTX3L |
|---|---|
| Gene Full Name | Deltex E3 Ubiquitin Ligase 3L |
| Background | Enables several functions, including STAT family protein binding activity; ubiquitin-like protein ligase binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of protein localization; and protein ubiquitination. Located in cytosol; lysosome; and nucleoplasm. Part of protein-containing complex. Colocalizes with early endosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | In association with PARP9, plays a role in antiviral responses by mediating 'Lys-48'-linked ubiquitination of encephalomyocarditis virus (EMCV) and human rhinovirus (HRV) C3 proteases and thus promoting their proteasomal-mediated degradation. [Uniprot] |
| Cellular Localization | Cytoplasm, Endosome, Lysosome, Membrane, Nucleus. [Uniprot] |
| PTM | Acetylation, Phosphoprotein, Ubl conjugation. [Uniprot] |
