ARG59616
anti-DUSP5 antibody
anti-DUSP5 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DUSP5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DUSP5 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 315-384 of Human DUSP5 (NP_004410.3). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 3.1.3.16; HVH3; Dual specificity protein phosphatase 5; Dual specificity protein phosphatase hVH3; EC 3.1.3.48; DUSP |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Raji | ||||
| Observed Size | 42 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q16690 Human Dual specificity protein phosphatase 5 |
|---|---|
| Gene Symbol | DUSP5 |
| Gene Full Name | dual specificity phosphatase 5 |
| Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008] |
| Function | Displays phosphatase activity toward several substrates. The highest relative activity is toward ERK1. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 42 kDa |
