ARG63192
anti-DUSP8 / HVH5 antibody
anti-DUSP8 / HVH5 antibody for Western blot and Human,Mouse,Rat
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes DUSP8 / HVH5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Predict Reactivity | Cow |
| Tested Application | WB |
| Specificity | This antibody is also expected to recognise the hypothetical human protein similar to dual specificity phosphatase 8 (XM_114902), which is virtually identical. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DUSP8 / HVH5 |
| Antigen Species | Human |
| Immunogen | AGDRLPRKVMDAK-C |
| Conjugation | Un-conjugated |
| Alternate Names | EC 3.1.3.48; EC 3.1.3.16; HVH-5; HB5; HVH8; Dual specificity protein phosphatase hVH-5; C11orf81; Dual specificity protein phosphatase 8 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O09112 Mouse Dual specificity protein phosphatase 8 Swiss-port # Q13202 Human Dual specificity protein phosphatase 8 |
|---|---|
| Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 66 kDa |
