ARG24146
anti-DUX4 antibody [P2B1] (HRP)
anti-DUX4 antibody [P2B1] (HRP) for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Developmental Biology antibody
Overview
| Product Description | HRP-conjugated Mouse Monoclonal antibody [P2B1] recognizes DUX4 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Specificity | This antibody recognizes human DUX4. Iut does not cross react with DUX4c. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | P2B1 |
| Isotype | IgG1 |
| Target Name | DUX4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around 76 aa (C-terminus) of Human DUX4 with glutathione-s-transferase (gst) tag. |
| Conjugation | HRP |
| Alternate Names | DUX4; DUX10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | DUX4L1 |
|---|---|
| Gene Full Name | double homeobox 4 like 1 |
| Background | DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues. |
| Cellular Localization | Nuclear |
| Highlight | Related products: anti-DUX4 antibody [P2B1] |
| Research Area | Developmental Biology antibody |
| Calculated MW | 45 kDa |
