ARG58462
anti-DYNC1I1 antibody
anti-DYNC1I1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DYNC1I1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DYNC1I1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-220 of Human DYNC1I1 (NP_001129028.1). |
| Conjugation | Un-conjugated |
| Alternate Names | DNCIC1; DNCI1; DH IC-1; Cytoplasmic dynein 1 intermediate chain 1; Dynein intermediate chain 1, cytosolic; Cytoplasmic dynein intermediate chain 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 85 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DYNC1I1 |
| Gene Full Name | dynein, cytoplasmic 1, intermediate chain 1 |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. [UniProt] |
| Cellular Localization | Cytoplasm, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole. [UniProt] |
| Calculated MW | 73 kDa |
