ARG41319
anti-Deptor antibody
anti-Deptor antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Deptor |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Specificity | At least three isoforms of Deptor are known to exist. This antibody will detect all three isoforms. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Deptor |
| Antigen Species | Human |
| Immunogen | A 16 amino acid peptide within aa. 220-270 of Human Deptor. |
| Conjugation | Un-conjugated |
| Alternate Names | DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEPDC6; DEP.6 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse liver | ||||
| Observed Size | ~ 46 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q570Y9 Mouse DEP domain-containing mTOR-interacting protein |
|---|---|
| Gene Symbol | DEPTOR |
| Gene Full Name | DEP domain containing MTOR-interacting protein |
| Function | Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. [UniProt] |
| Calculated MW | 46 kDa |
| PTM | Phosphorylated. Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2. [UniProt] |
