ARG57039

anti-EDAR antibody [19E8]

anti-EDAR antibody [19E8] for Western blot,Flow cytometry and Human

Overview

Product Description Mouse Monoclonal antibody [19E8] recognizes EDAR
Tested Reactivity Hu
Tested Application FACS, WB
Host Mouse
Clonality Monoclonal
Clone 19E8
Isotype IgG2a, kappa
Target Name EDAR
Antigen Species Human
Immunogen Recombinant fragment around aa. 27-448 of Human EDAR.
Conjugation Un-conjugated
Alternate Names ECTD10B; Ectodermal dysplasia receptor; DL; ECTD10A; EDA1R; Tumor necrosis factor receptor superfamily member EDAR; ED1R; Downless homolog; Ectodysplasin-A receptor; ED5; HRM1; ED3; EDA3; Anhidrotic ectodysplasin receptor 1; EDA-A1R; EDA-A1 receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10913 Human EDAR

Swiss-port # Q9UNE0 Human Tumor necrosis factor receptor superfamily member EDAR

Gene Symbol EDAR
Gene Full Name ectodysplasin A receptor
Background This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Function Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. [UniProt]
Calculated MW 49 kDa