ARG63299

anti-EDD1 / HYD antibody

anti-EDD1 / HYD antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody; Gene Regulation antibody

Overview

Product Description

Goat Polyclonal antibody recognizes EDD1 / HYD

Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Pig
Tested Application IHC-P
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name EDD1 / HYD
Antigen Species Human
Immunogen C-LAIKTKNFGFV
Conjugation Un-conjugated
Alternate Names HYD; EDD; EC 6.3.2.-; E3 ubiquitin-protein ligase, HECT domain-containing 1; DD5; E3 ubiquitin-protein ligase UBR5; Hyperplastic discs protein homolog; EDD1; hHYD; Progestin-induced protein

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1 - 2 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51366 Human UBR5

Swiss-port # O95071 Human E3 ubiquitin-protein ligase UBR5

Background This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Gene Regulation antibody
Calculated MW 309 kDa