ARG59801

anti-EFTUD2 antibody

anti-EFTUD2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Immunoprecipitation and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes EFTUD2
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name EFTUD2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-205 of Human EFTUD2 (NP_004238.3).
Conjugation Un-conjugated
Alternate Names Snrp116; 116 kDa U5 small nuclear ribonucleoprotein component; Snu114; U5-116 kDa; U5-116KD; Elongation factor Tu GTP-binding domain-containing protein 2; MFDGA; U5 snRNP-specific protein, 116 kDa; SNU114 homolog; SNRNP116; MFDM; hSNU114

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:100
IHC-P1:50 - 1:200
IP1:20 - 1:50
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse spleen and HeLa
Observed Size 120 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20624 Mouse EFTUD2

GeneID: 9343 Human EFTUD2

Swiss-port # O08810 Mouse 116 kDa U5 small nuclear ribonucleoprotein component

Swiss-port # Q15029 Human 116 kDa U5 small nuclear ribonucleoprotein component

Gene Symbol EFTUD2
Gene Full Name elongation factor Tu GTP binding domain containing 2
Background This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Function Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 109 kDa