ARG64290

anti-EGR2 antibody

anti-EGR2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Gene Regulation antibody; Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes EGR2
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name EGR2
Antigen Species Human
Immunogen HGTAGPDRKPFPC
Conjugation Un-conjugated
Alternate Names KROX20; Zinc finger protein Krox-20; EC 6.3.2.-; CMT1D; Early growth response protein 2; EGR-2; AT591; E3 SUMO-protein ligase EGR2; CMT4E

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay - dependent
WB2 - 6 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1959 Human EGR2

Swiss-port # P11161 Human E3 SUMO-protein ligase EGR2

Background The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Research Area Gene Regulation antibody; Neuroscience antibody
Calculated MW 50 kDa
PTM Ubiquitinated by WWP2 leading to proteasomal degradation.