ARG43779

anti-ELOVL7 antibody

anti-ELOVL7 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes ELOVL7
Tested Reactivity Hu, Ms
Predict Reactivity Bov, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ELOVL7
Antigen Species Human
Immunogen Synthetic peptide (15 aa) within aa. 40-90 of Human ELOVL7.
Conjugation Un-conjugated
Protein Full Name Elongation of very long chain fatty acids protein 7
Alternate Names ELOVL7; ELOVL Fatty Acid Elongase 7; Elongation Of Very Long Chain Fatty Acids Protein 7; Very Long Chain 3-Ketoacyl-CoA Synthase 7; Very Long Chain 3-Oxoacyl-CoA Synthase 7; 3-Keto Acyl-CoA Synthase ELOVL7; ELOVL FA Elongase 7; ELOVL Family Member 7, Elongation Of Long Chain Fatty Acids (Yeast); ELOVL Family Member 7, Elongation Of Long Chain Fatty Acids

Application Instructions

Predict Reactivity Note Rat (100%), Bovine (100%)
Application Suggestion
Tested Application Dilution
IHC-P5 μg/ml - 20 μg/ml
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human Liver tissue
Observed Size 33-38 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 74559 Mouse ELOVL7

GeneID: 79993 Human ELOVL7

Swiss-port # A1L3X0 Human Elongation of very long chain fatty acids protein 7

Swiss-port # Q9D2Y9 Mouse Elongation of very long chain fatty acids protein 7

Gene Symbol ELOVL7
Gene Full Name ELOVL fatty acid elongase 7
Background ELOVL7 enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation, saturated fatty acid; and very long-chain fatty acid biosynthetic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. [UniProt]
Calculated MW 33.3 kDa