ARG44148

anti-EMR1 F4 / 80 antibody

anti-EMR1 F4 / 80 antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat

Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody

Overview

Product Description Rabbit Polyclonal recognizes EMR1 F4 / 80
Tested Reactivity Ms, Rat
Tested Application IHC-P
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name EMR1 F4 / 80
Antigen Species Mouse
Immunogen Mouse EMR1 F4/80 recombinant protein (Position: G27-S230).
Conjugation Un-conjugated

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2 - 5 µg/ml
Application Note The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% sodium azide, 50% glycerol and 1 mg/ml BSA
Preservative 0.02% sodium azide
Stabilizer 50% glycerol and 1 mg/ml BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 13733 Mouse ADGRE1

GeneID: 316137 Rat ADGRE1

Swiss-port # Q5Y4N8 Rat Adhesion G protein-coupled receptor E2

Swiss-port # Q61549 Mouse Adhesion G protein-coupled receptor E1

Gene Symbol Adgre1
Gene Full Name adhesion G protein-coupled receptor E1
Background EMR1 F4/80 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Function EMR1 F4/80: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [UniProt]
Highlight Related Antibody Duos and Panels:
ARG30326 Inflammatory Cell Antibody Panel (for mouse)
Related products:
EMR1 F4/80 antibodies; EMR1 F4/80 Duos / Panels; Anti-Rat IgG secondary antibodies;
Related news:
Exploring Antiviral Immune Response
Research Area Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody
Calculated MW 98 kDa