ARG44148
anti-EMR1 F4 / 80 antibody
anti-EMR1 F4 / 80 antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat
Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody
Overview
Product Description | Rabbit Polyclonal recognizes EMR1 F4 / 80 |
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Tested Reactivity | Ms, Rat |
Tested Application | IHC-P |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | EMR1 F4 / 80 |
Antigen Species | Mouse |
Immunogen | Mouse EMR1 F4/80 recombinant protein (Position: G27-S230). |
Conjugation | Un-conjugated |
Application Instructions
Application Suggestion |
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Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS, 0.02% sodium azide, 50% glycerol and 1 mg/ml BSA |
Preservative | 0.02% sodium azide |
Stabilizer | 50% glycerol and 1 mg/ml BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q5Y4N8 Rat Adhesion G protein-coupled receptor E2 Swiss-port # Q61549 Mouse Adhesion G protein-coupled receptor E1 |
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Gene Symbol | Adgre1 |
Gene Full Name | adhesion G protein-coupled receptor E1 |
Background | EMR1 F4/80 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
Function | EMR1 F4/80: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [UniProt] |
Highlight | Related Antibody Duos and Panels: ARG30326 Inflammatory Cell Antibody Panel (for mouse) Related products: EMR1 F4/80 antibodies; EMR1 F4/80 Duos / Panels; Anti-Rat IgG secondary antibodies; Related news: Exploring Antiviral Immune Response |
Research Area | Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody |
Calculated MW | 98 kDa |