ARG22471
anti-EMR1 F4/80 antibody [Cl:A3-1] (APC)
anti-EMR1 F4/80 antibody [Cl:A3-1] (APC) for Flow cytometry and Mouse
Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody
Overview
| Product Description | APC-conjugated Rat Monoclonal antibody [Cl:A3-1] recognizes EMR1 F4/80 This antibody recognizes the murine F4/80 antigen, a 160 kD cell surface glycoprotein, member of the EGF-TM7 family. |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | Cl:A3-1 |
| Isotype | IgG2b |
| Target Name | EMR1 F4/80 |
| Antigen Species | Mouse |
| Immunogen | Thioglycollate stimulated peritoneal macrophages from C57BL/6 mice. |
| Conjugation | APC |
| Alternate Names | EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EMR1; Adhesion G protein-coupled receptor E1; EGF-like module receptor 1; TM7LN3 |
Application Instructions
| Application Suggestion |
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| Application Note | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose. |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 1% BSA and 5% Sucrose |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q61549 Mouse Adhesion G protein-coupled receptor E1 |
|---|---|
| Gene Symbol | Adgre1 |
| Gene Full Name | adhesion G protein-coupled receptor E1 |
| Background | EMR1 F4/80 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Function | EMR1 F4/80: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [UniProt] |
| Highlight | Related products: EMR1 F4/80 antibodies; EMR1 F4/80 Duos / Panels; Anti-Rat IgG secondary antibodies; Related news: Exploring Antiviral Immune Response |
| Research Area | Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody |
| Calculated MW | 98 kDa |
