ARG64627
anti-ERAP2 antibody
anti-ERAP2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Immune System antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ERAP2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Dog |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ERAP2 |
| Antigen Species | Human |
| Immunogen | C-QYLKKFSYRNAKND |
| Conjugation | Un-conjugated |
| Alternate Names | Endoplasmic reticulum aminopeptidase 2; Leukocyte-derived arginine aminopeptidase; L-RAP; LRAP; EC 3.4.11.- |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6P179 Human Endoplasmic reticulum aminopeptidase 2 |
|---|---|
| Background | Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).[supplied by OMIM, Mar 2008] |
| Research Area | Cell Biology and Cellular Response antibody; Immune System antibody |
| Calculated MW | 110 kDa |
| PTM | N-glycosylated. |
