ARG56532
anti-FABP2 / Intestinal FABP antibody
anti-FABP2 / Intestinal FABP antibody for Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FABP2 / Intestinal FABP |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | WB |
| Specificity | This antibody does not react to FABP1, FABP3 and FABP4. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FABP2 / Intestinal FABP |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 33-40 of Human Intestinal FABP. |
| Conjugation | Un-conjugated |
| Alternate Names | Intestinal-type fatty acid-binding protein; I-FABP; Fatty acid-binding protein, intestinal; Fatty acid-binding protein 2; FABPI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P02693 Rat Fatty acid-binding protein, intestinal Swiss-port # P12104 Human Fatty acid-binding protein, intestinal |
|---|---|
| Gene Symbol | FABP2 |
| Gene Full Name | fatty acid binding protein 2, intestinal |
| Background | The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] |
| Function | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. [UniProt] |
| Calculated MW | 15 kDa |
