ARG43430
anti-FAM120A antibody
anti-FAM120A antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
Product Description | Mouse Monoclonal antibody recognizes FAM120A |
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Tested Reactivity | Hu |
Tested Application | IHC-P, WB |
Host | Mouse |
Clonality | Monoclonal |
Clone | 1501CT803.19.85.5 |
Isotype | IgG1, kappa |
Target Name | FAM120A |
Antigen Species | Human |
Immunogen | Recombinant protein of Human FAM120A. |
Conjugation | Un-conjugated |
Alternate Names | Constitutive coactivator of PPAR-gamma-like protein 1; Protein FAM120A; C9orf10; Oxidative stress-associated Src activator; DNAPTP5; DNAPTP1; OSSA |
Application Instructions
Application Suggestion |
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Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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Positive Control | MCF7 | ||||||
Observed Size | ~ 135 kDa |
Properties
Form | Liquid |
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Purification | Purification with Protein G. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9NZB2 Human Constitutive coactivator of PPAR-gamma-like protein 1 |
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Gene Symbol | FAM120A |
Gene Full Name | family with sequence similarity 120A |
Function | May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. [UniProt] |
Cellular Localization | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure. [UniProt] |
Calculated MW | 122 kDa |
PTM | Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. [UniProt] |