ARG40027
anti-FAM208A antibody
anti-FAM208A antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FAM208A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FAM208A |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 700-1000 of Human FAM208A (NP_001106207.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Retinoblastoma-associated protein RAP140; Transgene activation suppressor protein; RAP140; C3orf63; CTCL tumor antigen se89-1; se89-1; Protein TASOR |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | U-87 MG | ||||
| Observed Size | 190 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FAM208A |
| Gene Full Name | family with sequence similarity 208, member A |
| Function | Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. [UniProt] |
| Cellular Localization | Nucleus. Chromosome. Note=Localizes to chromatin. [UniProt] |
| Calculated MW | 189 kDa |
| PTM | Asn-1105 may be N-glycosylated; however as this position is probably not extracellular, the in vivo relevance is not proven. [UniProt] |
