ARG63516
anti-FAPP2 / PLEKHA8 antibody
anti-FAPP2 / PLEKHA8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes FAPP2 / PLEKHA8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FAPP2 / PLEKHA8 |
| Antigen Species | Human |
| Immunogen | C-DIQTALRNPTENT |
| Conjugation | Un-conjugated |
| Alternate Names | Phosphatidylinositol-four-phosphate adapter protein 2; Serologically defined breast cancer antigen NY-BR-86; hFAPP2; PH domain-containing family A member 8; FAPP-2; FAPP2; Pleckstrin homology domain-containing family A member 8; Phosphoinositol 4-phosphate adapter protein 2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96JA3 Human Pleckstrin homology domain-containing family A member 8 |
|---|---|
| Gene Symbol | PLEKHA8 |
| Gene Full Name | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 |
| Function | Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. [UniProt] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 58 kDa |
