ARG64728

anti-FBXL10 / PCCX2 antibody

anti-FBXL10 / PCCX2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes FBXL10 / PCCX2
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application IHC-P
Specificity This antibody is expected to recognize isoform a (NP_115979.3) only.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name FBXL10 / PCCX2
Antigen Species Human
Immunogen C-FGQVEEKLLQKLS
Conjugation Un-conjugated
Alternate Names JHDM1B; EC 1.14.11.27; FBXL10; CXXC-type zinc finger protein 2; F-box and leucine-rich repeat protein 10; CXXC2; JmjC domain-containing histone demethylation protein 1B; F-box/LRR-repeat protein 10; PCCX2; Lysine-specific demethylase 2B; [Histone-H3]-lysine-36 demethylase 1B; Fbl10; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; Protein JEMMA; Protein-containing CXXC domain 2; F-box protein FBL10

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 84678 Human KDM2B

Swiss-port # Q8NHM5 Human Lysine-specific demethylase 2B

Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody
Calculated MW 153 kDa