ARG58597
anti-FCER1G antibody
anti-FCER1G antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FCER1G |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Bov, Rat, Mk, Pig |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FCER1G |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 60-86 of Human FCER1G. |
| Conjugation | Un-conjugated |
| Alternate Names | FCRG; High affinity immunoglobulin epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; FcRgamma; Fc receptor gamma-chain; FceRI gamma; Fc-epsilon RI-gamma |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human spleen |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P30273 Human High affinity immunoglobulin epsilon receptor subunit gamma |
|---|---|
| Gene Symbol | FCER1G |
| Gene Full Name | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| Background | The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008] |
| Function | Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 10 kDa |
