ARG58669
anti-FCGRT antibody
anti-FCGRT antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FCGRT |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FCGRT |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 25-300 of Human FCGRT (NP_004098.1). |
| Conjugation | Un-conjugated |
| Alternate Names | FCRN; IgG receptor FcRn large subunit p51; alpha-chain; Neonatal Fc receptor; FcRn; IgG Fc fragment receptor transporter alpha chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse kidney | ||||
| Observed Size | 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P55899 Human IgG receptor FcRn large subunit p51 Swiss-port # Q61559 Mouse IgG receptor FcRn large subunit p51 |
|---|---|
| Gene Symbol | FCGRT |
| Gene Full Name | Fc fragment of IgG, receptor, transporter, alpha |
| Background | This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| Function | Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. [UniProt] |
| Cellular Localization | Cell membrane, Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 40 kDa |
