ARG44661
anti-FGFBP1 antibody
anti-FGFBP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
Product Description | Mouse Monoclonal antibody recognizes FGFBP1 |
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Tested Reactivity | Hu |
Tested Application | IHC-P, IP, WB |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Target Name | FGFBP1 |
Antigen Species | Human |
Conjugation | Un-conjugated |
Alternate Names | FGFBP1; Fibroblast Growth Factor Binding Protein 1; HBP17; FGFBP; 17 KDa Heparin-Binding Growth Factor-Binding Protein; Fibroblast Growth Factor-Binding Protein 1; 17 KDa HBGF-Binding Protein; FGF-Binding Protein 1; FGF-BP1; FGFBP-1; FGF-BP; Heparin-Binding Growth Factor Binding Protein; HBp17 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Protein A purification |
Buffer | PBS with 0.09% sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q14512 Human Fibroblast growth factor-binding protein 1 |
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Gene Symbol | FGFBP1 |
Gene Full Name | Fibroblast Growth Factor Binding Protein 1 |
Background | This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] |
Function | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. [UniProt] |
Cellular Localization | Cell membrane, Membrane, Secreted. [UniProt] |
Calculated MW | 26 kDa |
PTM | Disulfide bond, Glycoprotein. [UniProt] |