ARG44661

anti-FGFBP1 antibody

anti-FGFBP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody recognizes FGFBP1
Tested Reactivity Hu
Tested Application IHC-P, IP, WB
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Target Name FGFBP1
Antigen Species Human
Conjugation Un-conjugated
Alternate Names FGFBP1; Fibroblast Growth Factor Binding Protein 1; HBP17; FGFBP; 17 KDa Heparin-Binding Growth Factor-Binding Protein; Fibroblast Growth Factor-Binding Protein 1; 17 KDa HBGF-Binding Protein; FGF-Binding Protein 1; FGF-BP1; FGFBP-1; FGF-BP; Heparin-Binding Growth Factor Binding Protein; HBp17

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P7.5 µg/mL
IP10 µg/mL
WB1 µg/mL
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9982 Human FGFBP1

Swiss-port # Q14512 Human Fibroblast growth factor-binding protein 1

Gene Symbol FGFBP1
Gene Full Name Fibroblast Growth Factor Binding Protein 1
Background This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
Function Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. [UniProt]
Cellular Localization Cell membrane, Membrane, Secreted. [UniProt]
Calculated MW 26 kDa
PTM Disulfide bond, Glycoprotein. [UniProt]