ARG41868
anti-FLOT2 / Flotillin 2 antibody
anti-FLOT2 / Flotillin 2 antibody for ICC/IF and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FLOT2 / Flotillin 2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FLOT2 / Flotillin 2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 239-428 of Human FLOT2 / Flotillin 2. (NP_004466.2) |
| Conjugation | Un-conjugated |
| Alternate Names | M17S1; ESA1; Membrane component chromosome 17 surface marker 1; ECS-1; Epidermal surface antigen; ECS1; ESA; Flotillin-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FLOT2 |
| Gene Full Name | flotillin 2 |
| Background | Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008] |
| Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. [UniProt] |
| Cellular Localization | Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane-associated protein of caveolae. [UniProt] |
| Calculated MW | 47 kDa |
| PTM | ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells. [UniProt] |
