ARG41868

anti-FLOT2 / Flotillin 2 antibody

anti-FLOT2 / Flotillin 2 antibody for ICC/IF and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes FLOT2 / Flotillin 2
Tested Reactivity Hu
Tested Application ICC/IF
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FLOT2 / Flotillin 2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 239-428 of Human FLOT2 / Flotillin 2. (NP_004466.2)
Conjugation Un-conjugated
Alternate Names M17S1; ESA1; Membrane component chromosome 17 surface marker 1; ECS-1; Epidermal surface antigen; ECS1; ESA; Flotillin-2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:10 - 1:100
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2319 Human FLOT2

Swiss-port # Q14254 Human Flotillin-2

Gene Symbol FLOT2
Gene Full Name flotillin 2
Background Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. [UniProt]
Cellular Localization Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane-associated protein of caveolae. [UniProt]
Calculated MW 47 kDa
PTM ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells. [UniProt]