ARG52282

anti-FOX1 antibody [1G10]

anti-FOX1 antibody [1G10] for ICC/IF,Western blot and Human,Mouse,Rat,Bovine

Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody

Overview

Product Description Mouse Monoclonal antibody [1G10] recognizes FOX1
Tested Reactivity Hu, Ms, Rat, Bov
Tested Application ICC/IF, WB
Host Mouse
Clonality Monoclonal
Clone 1G10
Isotype IgG1
Target Name FOX1
Antigen Species Human
Immunogen Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli
Conjugation Un-conjugated
Alternate Names RNA binding protein fox-1 homolog 1; HRNBP1; Ataxin-2-binding protein 1; Hexaribonucleotide-binding protein 1; 2BP1; FOX-1; FOX1; Fox-1 homolog A; A2BP1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:500
WB1:5,000
Application Note Specific for the ~46/48k FOX1 protein doublet.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity Purified
Buffer PBS and 10 mM Sodium azide
Preservative 10 mM Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 268859 Mouse RBFOX1

GeneID: 521304 Bovine RBFOX1

GeneID: 54715 Human RBFOX1

Gene Symbol RBFOX1
Gene Full Name RNA binding protein, fox-1 homolog (C. elegans) 1
Background FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008).
Research Area Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
Calculated MW 43 kDa