ARG53038
anti-FOXA1 / HNF3A antibody [SP88]
anti-FOXA1 / HNF3A antibody [SP88] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody
Overview
| Product Description | Rabbit Monoclonal antibody [SP88] recognizes FOXA1 / HNF3A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SP88 |
| Isotype | IgG |
| Target Name | FOXA1 / HNF3A |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from near C-terminus of human FOXA1 protein. |
| Conjugation | Un-conjugated |
| Alternate Names | TCF3A; Forkhead box protein A1; Hepatocyte nuclear factor 3-alpha; TCF-3A; HNF-3A; HNF-3-alpha; HNF3A; Transcription factor 3A |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Incubation Time: 30 min at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Prostate |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by protein A/G |
| Buffer | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| Preservative | < 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. |
| Cellular Localization | Nucleus in Breast Carcinoma, Prostate. Cytoplasm in most malignancies. |
| Research Area | Gene Regulation antibody |
| Calculated MW | 49 kDa |
