ARG63689

anti-FOXN1 antibody

anti-FOXN1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Gene Regulation antibody; Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes FOXN1
Tested Reactivity Hu
Tested Application IHC-P
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name FOXN1
Antigen Species Human
Immunogen C-SVYLSPSSKPVALA
Conjugation Un-conjugated
Alternate Names FKHL20; WHN; Forkhead box protein N1; Winged-helix transcription factor nude; RONU

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P4 - 6 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8456 Human FOXN1

Swiss-port # O15353 Human Forkhead box protein N1

Background Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody; Immune System antibody
Calculated MW 69 kDa