ARG43900
anti-FOXO3A antibody
anti-FOXO3A antibody for ELISA,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FOXO3A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FOXO3A |
| Antigen Species | Human |
| Immunogen | Human FOXO3A recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Forkhead box protein O3 |
| Alternate Names | FOXO3; Forkhead Box O3; AF6q21; FKHRL1; FOXO3A; FOXO2; Forkhead In Rhabdomyosarcoma-Like 1; Forkhead Box Protein O3; Forkhead, Drosophila, Homolog Of, In Rhabdomyosarcoma-Like 1; Forkhead Homolog (Rhabdomyosarcoma) Like 1; Forkhead Box O3A; AF6q21 Protein; FKHRL1P2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FOXO3 |
| Gene Full Name | Forkhead Box O3 |
| Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. |
| Function | Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophagy |
| Cellular Localization | Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus |
| Calculated MW | 71 kDa |
| PTM | Acetylation, Methylation, Phosphoprotein, Ubl conjugation |
