ARG66792

anti-FPR2 / FPRL1 antibody

anti-FPR2 / FPRL1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes FPR2 / FPRL1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FPR2 / FPRL1
Antigen Species Human
Immunogen Synthetic peptide between aa. 130-210 of Human FPR2 / FPRL1.
Conjugation Un-conjugated
Alternate Names FMLP-related receptor I; N-formyl peptide receptor 2; RFP; FPRL1; Lipoxin A4 receptor; FPRH1; ALXR; FPRH2; HM63; FMLP-R-I; FPR2A; LXA4 receptor; FMLPX; Formyl peptide receptor-like 1; LXA4R; FMLP-R-II

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SW480
Observed Size ~ 39 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2358 Human FPR2

Swiss-port # P25090 Human N-formyl peptide receptor 2

Gene Symbol FPR2
Gene Full Name formyl peptide receptor 2
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity). [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 39 kDa