ARG41447

anti-FTCD / 58K Golgi protein antibody

anti-FTCD / 58K Golgi protein antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,Flow cytometry and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes FTCD / 58K Golgi protein
Tested Reactivity Hu
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FTCD / 58K Golgi protein
Antigen Species Human
Immunogen Synthetic peptide of Human FTCD / 58K Golgi protein.
Conjugation Un-conjugated
Alternate Names EC 2.1.2.5; LCHC1; Formiminotetrahydrofolate cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; Glutamate formiminotransferase; Glutamate formyltransferase; FTCD; EC 4.3.1.4

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:100
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human fetal liver
Observed Size ~ 58 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10841 Human FTCD

Swiss-port # O95954 Human Formimidoyltransferase-cyclodeaminase

Gene Symbol FTCD
Gene Full Name formimidoyltransferase cyclodeaminase
Background The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]
Function Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.

Binds and promotes bundling of vimentin filaments originating from the Golgi. [UniProt]
Cellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Note=More abundantly located around the mother centriole. [UniProt]
Calculated MW 59 kDa