ARG64013

anti-FXR1 antibody

anti-FXR1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse

Gene Regulation antibody; Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes FXR1
Tested Reactivity Hu, Ms
Predict Reactivity Cow, Rat, Dog
Tested Application FACS, ICC/IF, WB
Specificity This antibody is expected to recognise all reported isoforms (NP_005078.2, NP_001013456.1 and NP_001013457.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name FXR1
Antigen Species Human
Immunogen C-RIEGDNENKLPRED
Conjugation Un-conjugated
Alternate Names hFXR1p; FXR1P; Fragile X mental retardation syndrome-related protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µg/ml
ICC/IF10 µg/ml
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14359 Mouse FXR1

GeneID: 8087 Human FXR1

Swiss-port # P51114 Human Fragile X mental retardation syndrome-related protein 1

Swiss-port # Q61584 Mouse Fragile X mental retardation syndrome-related protein 1

Background The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody; Immune System antibody
Calculated MW 70 kDa
PTM Arg-445 is dimethylated, probably to asymmetric dimethylarginine.