ARG64432

anti-FZD4 / Frizzled 4 antibody

anti-FZD4 / Frizzled 4 antibody for Western blot and Human

Cancer antibody; Developmental Biology antibody; Gene Regulation antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes FZD4 / Frizzled 4
Tested Reactivity Hu
Predict Reactivity Rat
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name FZD4 / Frizzled 4
Antigen Species Human
Immunogen DEEERRCDPIRIS
Conjugation Un-conjugated
Alternate Names Fz4; FzE4; CD344; CD antigen CD344; Frizzled-4; Fz-4; hFz4; GPCR; FZD4S; FEVR; EVR1

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8322 Human FZD4

Swiss-port # Q9ULV1 Human Frizzled-4

Background This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
Research Area Cancer antibody; Developmental Biology antibody; Gene Regulation antibody; Signaling Transduction antibody
Calculated MW 60 kDa
PTM Ubiquitinated by ZNRF3, leading to its degradation by the proteasome.