ARG22666
anti-Feline Leukaemia Virus p15E antibody [PF6J-2A1]
anti-Feline Leukaemia Virus p15E antibody [PF6J-2A1] for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Virus
Overview
| Product Description | Mouse Monoclonal antibody [PF6J-2A1] recognizes Feline Leukaemia Virus p15E This antibody recognizes an epitope within the amino-terminal domain of both the 20 kDa full-length (including intracellular sequence), and the 15k Da truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein. Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE. |
|---|---|
| Tested Reactivity | Virus |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PF6J-2A1 |
| Isotype | IgG2a |
| Target Name | Feline Leukaemia Virus p15E |
| Antigen Species | Virus |
| Conjugation | Un-conjugated |
Application Instructions
| Application Suggestion |
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| Application Note | WB: This antibody detects bands of ~ 15 kDa and 20 kDa under reducing conditions. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 0.05% Sodium azide. |
| Preservative | 0.05% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
