ARG64344

anti-GALNS antibody

anti-GALNS antibody for Western blot and Human

Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes GALNS
Tested Reactivity Hu
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GALNS
Antigen Species Human
Immunogen C-TTHNLEDHTKLP
Conjugation Un-conjugated
Alternate Names MPS4A; EC 3.1.6.4; Chondroitinsulfatase; GAS; N-acetylgalactosamine-6-sulfatase; GalNAc6S sulfatase; GalN6S; Chondroitinase; GALNAC6S; N-acetylgalactosamine-6-sulfate sulfatase; Galactose-6-sulfate sulfatase

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.01 - 0.03 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2588 Human GALNS

Swiss-port # P34059 Human N-acetylgalactosamine-6-sulfatase

Background This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody
Calculated MW 58 kDa
PTM The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.