ARG58728

anti-GALNT2 antibody

anti-GALNT2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes GALNT2
Tested Reactivity Hu, Rat
Tested Application ICC/IF, IHC-P
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GALNT2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 442-571 of Human GALNT2 (NP_004472.1).
Conjugation Un-conjugated
Alternate Names Protein-UDP acetylgalactosaminyltransferase 2; EC 2.4.1.41; pp-GaNTase 2; GalNAc-T2; Polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; Polypeptide GalNAc transferase 2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:100
IHC-P1:50 - 1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 65 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2590 Human GALNT2

Swiss-port # Q10471 Human Polypeptide N-acetylgalactosaminyltransferase 2

Gene Symbol GALNT2
Gene Full Name polypeptide N-acetylgalactosaminyltransferase 2
Background This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. [UniProt]
Cellular Localization Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Secreted. [UniProt]
Calculated MW 65 kDa