ARG58738

anti-GALNT3 antibody

anti-GALNT3 antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes GALNT3
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GALNT3
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-140 of Human GALNT3 (NP_004473.2).
Conjugation Un-conjugated
Alternate Names HHS; Protein-UDP acetylgalactosaminyltransferase 3; EC 2.4.1.41; pp-GaNTase 3; HFTC; Polypeptide GalNAc transferase 3; GalNAc-T3; Polypeptide N-acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control BT-474
Observed Size 73 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14425 Mouse GALNT3

GeneID: 2591 Human GALNT3

Swiss-port # P70419 Mouse Polypeptide N-acetylgalactosaminyltransferase 3

Swiss-port # Q14435 Human Polypeptide N-acetylgalactosaminyltransferase 3

Gene Symbol GALNT3
Gene Full Name polypeptide N-acetylgalactosaminyltransferase 3
Background This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities. [provided by RefSeq, Jul 2008]
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis. [UniProt]
Cellular Localization Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein. [UniProt]
Calculated MW 73 kDa