ARG55132
anti-GATA3 antibody
anti-GATA3 antibody for Flow cytometry,ICC/IF,Western blot and Human
Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Immune System antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes GATA3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1259CT707.136.102 |
| Isotype | IgG2b, kappa |
| Target Name | GATA3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human GATA3. |
| Conjugation | Un-conjugated |
| Alternate Names | Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3; HDR; HDRS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HL-60 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P23771 Human Trans-acting T-cell-specific transcription factor GATA-3 |
|---|---|
| Gene Symbol | GATA3 |
| Gene Full Name | GATA binding protein 3 |
| Background | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] |
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. [UniProt] |
| Cellular Localization | Nucleus. |
| Research Area | Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Immune System antibody |
| Calculated MW | 48 kDa |
